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Hydroxychloroquine for COVID-19: What's the Evidence?

F. Perry Wilson, MD, MSCE

Coronavirus has caused us to reevaluate so many things. I'm doing renal consults today from my office, only physically going to see patients if absolutely necessary—something unthinkable just a few weeks ago. It's also causing us to reevaluate what we mean by "evidenced-based medicine." In the days before the pandemic, many of us were of the "randomized trial or bust" mindset, often dismissing good observational studies without rigorous review, and likewise embracing even suspect studies just because they happened to be randomized.

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