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Antibody Cocktail Seems to Prevent Family Spread of Disease in COVID-19

A one-time injection of the monoclonal antibody cocktail casirivimab with imdevimab (REGEN-COV), taken within 72 hours of a household member's diagnosis with SARS-CoV-2, prevented 100% of COVID-19 illness, 100% of high SARS-CoV-2 viral loads, and cut length of asymptomatic infection to 1 week.

"It's fantastic news," said Rajesh Gandhi, MD, an infectious disease physician at Massachusetts General Hospital and Harvard Medical School, who has been treating people seriously ill with COVID-19 since the pandemic began a year ago in Boston. "For individuals who, for whatever reason, don't get the vaccine or decline the vaccine or haven't yet gotten the vaccine, it's really proof that antibodies can prevent disease" in COVID-19.

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